F3001 – CENPB-FAM – 5 nmole

$295.00

Catalog Number: F3001
Product Name: CENPB-FAM
Description: CENPB Pan-Centromere PNA Probe, FAM labeled
Size: 5 nmole
Label: FAM (Green fluorescence)
Target: ATTCGTTGGAAACGGGA (CENPB-binding region of centromere minor satellite DNA)
Form: Lyophilized
Application: Centromere FISH, karyotyping, Q-FISH control
Storage: –20°C, protect from light

Category:

Product Description

CENPB-FAM is a pan-centromere PNA probe targeting human centromeric regions, specifically designed to bind CENPB DNA-binding sites. Labeled with FAM, a green fluorescent dye, this probe provides high-intensity signal and sharp resolution for chromosome identification in interphase and metaphase spreads.

CENPB-FAM is commonly used for karyotyping, aneuploidy detection, and genomic stability assays. Its PNA backbone provides unmatched specificity, low background, and robust hybridization even in complex genomic environments.

Each vial contains 5 nmole, which is usually good enough to stain more than 500 slides.

Key Features

  • Pan-centromere detection across all human chromosomes
  • Labeled with FAM for bright green signal
  • PNA design ensures high binding specificity and low background
  • Ideal for both metaphase and interphase FISH
  • Reliable hybridization under standard protocols
  • Compatible with clinical and research imaging systems

Applications

  • Whole-genome centromere mapping
  • Chromosome enumeration in cancer diagnostics
  • Prenatal and postnatal aneuploidy screening
  • Genetic stability monitoring in stem cell research
  • Comparative genomic hybridization
  • High-resolution karyotyping

What’s Included

  • 5 nmole CENPB-FAM PNA probe
  • FISH protocol and usage instructions
  • Access to technical support

Support

Need guidance for imaging centromeres in metaphase or interphase? Contact our technical team for probe setup and filter selection help.

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