F3003 – CENT-Cy3 – 5 nmole

$295.00

Catalog Number: F3003
Product Name: CENT-Cy3
Description: Centromere PNA Probe, Cy3 labeled
Size: 5 nmole
Label: Cy3 (Red fluorescence)
Target: AAACTAGACAGAAGCATT (Human alpha satellite)
Purity: >95% (HPLC)
Form: Lyophilized
Application: Centromere FISH, karyotyping, Q-FISH control
Storage: –20°C, protect from light

Category:

Product Description

CENT-Cy3 is a human centromere-specific PNA probe designed for fluorescence in situ hybridization (FISH). Labeled with Cy3, a bright red fluorophore, it enables the clear detection of centromeric regions on human chromosomes. This probe is ideal for chromosome enumeration, aneuploidy detection, and clinical karyotyping workflows.

Its synthetic PNA backbone provides enhanced binding affinity, resistance to nucleases, and strong signal-to-background contrast, outperforming traditional DNA-based probes in diagnostic and research settings.

Key Features

  • Specific to human centromeric DNA
  • Labeled with Cy3 for strong red signal
  • PNA chemistry offers excellent specificity and stability
  • Ideal for clinical and research-grade chromosome analysis
  • Compatible with multi-color FISH experiments
  • Validated in both metaphase and interphase spreads

Applications

  • Chromosomal enumeration in FISH
  • Karyotyping of human samples
  • Detection of aneuploidy and structural abnormalities
  • Clinical diagnostics and cancer screening
  • Genomic integrity assessment in stem cell lines
  • Fluorescent labeling in cytogenetics

What’s Included

  • 5 nmole CENT-Cy3 PNA probe
  • Reconstitution and usage guidelines
  • Technical support access

Support

Need help setting up your human centromere FISH assay? Contact our experts for filter guidance and signal optimization.

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