CS01-200 – SniperCas9 – High Fidelity Cas9 Protein with NLS – 200 µg

SniperCas9 is a next-generation high fidelity Cas9 protein engineered to minimize off-target activity in CRISPR genome editing. Provided as four 50 µg vials (200 µg total), this variant reconstitutes to 1 mg/ml and delivers 1200 pmol (6 µM × 200 µl). It is ideal for researchers requiring precision and specificity for in vivo or in vitro experiments.

Equipped with a nuclear localization signal (NLS), SniperCas9 ensures rapid nuclear import following delivery. The product is suitable for microinjection, electroporation, and lipofection, and is validated for RNP complex formation with synthetic sgRNAs.

Researchers trust SniperCas9 for sensitive cell editing, therapeutic model development, and any workflow requiring reduced off-target genome editing risks.

• High-fidelity Cas9 variant engineered to reduce off-target effects
• Delivered in 4 vials (50 µg each) for flexible experimental planning
• Reconstitutes to 1 mg/ml
• Enhanced targeting specificity with NLS-enabled nuclear entry
• Validated for embryo injection, stem cell editing, and RNP delivery
• Compatible with microinjection, electroporation, and lipofection

• Precise gene knockout or point mutation editing
• CRISPR-based therapeutic model generation
• Sensitive cell editing in human iPSCs or embryos
• Microinjection into zebrafish, mouse, or rat embryos
• Multiplex CRISPR experiments requiring high specificity
• Gene correction workflows in translational research

• 4 × 50 µg SniperCas9 high fidelity Cas9 protein
• Reconstitution instructions
• RNP complex formation guide
• Priority technical support access

Need help optimizing your delivery or selecting the best Cas9 variant? Contact our support team for expert assistance with experiment planning or troubleshooting.