IP01-25 – ITS-PNA-S – 25 nmole

ITS-PNA-S is a 25 nmole PNA blocker designed to bind and suppress amplification of the ITS2 rRNA region, a commonly overrepresented target in fungal PCR. By targeting the conserved sequence cgagggcacgtctgcctgg, ITS-PNA-S helps eliminate dominant ITS signals and improve nuclear gene detection in fungal DNA and RNA sequencing workflows.

The PNA backbone ensures high stability, resistance to enzymatic degradation, and sharp binding discrimination—making it ideal for fungal biodiversity studies, metagenomics, and PCR cleanup.

• Suppresses conserved fungal ITS2 rRNA sequences
• 25 nmole format for small-to-medium PCR workflows
• Enables detection of rare fungal nuclear DNA targets
• Minimizes off-target amplification during ITS-based assays
• Compatible with metagenomics and environmental DNA workflows
• Stable PNA structure resists nucleases and enhances precision

• PCR and qPCR suppression of fungal ITS2 rRNA
• High-precision fungal DNA and RNA profiling
• Biodiversity and ecological metagenomic studies
• Fungal microbiome analysis
• Environmental and clinical sample testing
• Pre-NGS rRNA depletion in fungal templates

• 25 nmole ITS-PNA-S oligo
• Full protocol and setup instructions
• Technical support for fungal rRNA suppression

Need help integrating this into your fungal NGS workflow? Reach out to our experts for PCR optimization and rRNA blocker setup.