G2001-10 – GR PNA-L – Globin Blocking PNA – 10 nmole

GR PNA-L is a 10 nmole large-scale set of 4 high-affinity PNA oligos targeting alpha and beta human globin mRNAs. By blocking the reverse transcription of these highly abundant transcripts, this set significantly improves RNA-seq depth and coverage of low-abundance genes from blood-derived RNA samples.

Built on peptide nucleic acid (PNA) chemistry, these oligos provide unmatched thermal stability, enzymatic resistance, and hybridization performance—making them ideal for clinical diagnostics, biomarker discovery, and high-throughput gene expression analysis.

• Includes 4 PNA oligos targeting globin mRNAs
• Large 10 nmole set for multiple RNA-seq runs
• Improves read distribution across diverse transcripts
• PNA-based design ensures high stability and binding accuracy
• Scalable for high-throughput RNA profiling and clinical studies
• Compatible with RT-PCR, cDNA synthesis, and NGS pipelines

• Large-scale blood RNA-seq analysis
• Reduction of high-abundance globin interference
• Improved detection of rare transcripts
• Clinical research and disease biomarker identification
• Integration with RNA-seq library prep workflows
• Pre-PCR depletion of unwanted transcripts

• 4 lyophilized PNA oligos (10 nmole total)
• Technical usage guide for RNA-seq workflows
• Access to RNA optimization and support resources

Questions about integrating this large-volume PNA set into your pipeline? Contact our RNA-seq experts for help with scale-up, protocol design, and troubleshooting.