F5002 – (CAG)5-Cy5 – 5 nmole

The (CAG)5-Cy5 probe is a highly specific PNA probe designed to detect CAG trinucleotide repeats, labeled with Cy5 for vivid far-red fluorescence. This probe is ideal for identifying repeat expansions in Myotonic Dystrophy Type 1 (DM1) and other repeat instability disorders using fluorescence in situ hybridization (FISH).

With its synthetic PNA structure, the probe offers strong hybridization, superior signal-to-noise ratio, and stability across experimental conditions. The Cy5 label enables multiplexing with green and orange fluorophores.

Each vial contains 5 nmole, which is usually good enough to stain more than 500 slides.

• Targets expanded (CAG)n repeats in genomic DNA
• Cy5 label for far-red imaging in multiplex assays
• PNA structure ensures strong hybridization and low background
• Compatible with clinical and research-grade FISH platforms
• Works in metaphase and interphase cell spreads
• Validated in DM1 and Huntington’s detection workflows

• Detection of CAG repeat expansions in DM1 and related disorders
• Chromosomal repeat visualization using FISH
• Genetic diagnostics and mutation screening
• Research in neurodegenerative disease pathways
• Multi-color probe studies using red/far-red fluorescence
• Complementary mapping with CTG probes

• 5 nmole (CAG)5-Cy5 PNA probe
• User guide for probe reconstitution and FISH
• Email and phone-based technical support

Need guidance on filter selection or co-hybridization setup? Contact our team to optimize your Cy5-labeled FISH experiments.