F3004 – CENPB-Alexa488 – 5 nmole

CENPB-Alexa488 is a pan-centromere PNA probe that binds to CENPB-binding DNA regions at human chromosome centromeres. It is labeled with Alexa Fluor 488, producing intense green fluorescence ideal for FISH applications requiring high-resolution centromere detection.

This probe combines PNA technology with advanced dye chemistry, ensuring superior hybridization, exceptional signal clarity, and minimal background noise—making it a reliable solution for cytogenetics, diagnostics, and research workflows.

Each vial contains 5 nmole, which is usually good enough to stain more than 500 slides.

• Pan-centromere detection using Alexa Fluor 488
• Brilliant green signal with high contrast
• PNA probe design offers low background and strong specificity
• Compatible with metaphase and interphase spreads
• Useful in clinical and research-based cytogenetics
• Stable long-term storage and repeat use

• Centromere visualization in high-resolution FISH
• Chromosome enumeration for diagnostics
• Prenatal/postnatal karyotyping
• Genome stability testing in stem cell research
• Cancer cytogenetics and mutation screening
• Automated or manual FISH image analysis

• 5 nmole CENPB-Alexa488 PNA probe
• FISH reconstitution and usage instructions
• Technical support resources

Need help setting up Alexa Fluor 488 for your FISH platform? Contact our team for filter recommendations and hybridization help.