F3004 – CENPB-Alexa488 – 5 nmole

CENPB-Alexa488 is a pan-centromere PNA probe that binds to CENPB binding DNA regions at human and mouse chromosome centromeres. It is labeled with Alexa Fluor 488, producing intense green fluorescence ideal for FISH applications requiring high-resolution centromere detection.

This probe combines PNA technology with advanced dye chemistry, ensuring superior hybridization, exceptional signal clarity, and minimal background noise—making it a reliable solution for cytogenetics, diagnostics, and research workflows.

Each vial contains 5 nmole, which is usually good enough to stain more than 500 slides.

• Pan-centromere detection using Alexa Fluor 488
• Brilliant green signal with high contrast
• PNA probe design offers low background and strong specificity
• Compatible with metaphase and interphase spreads
• Useful in clinical and research-based cytogenetics
• Stable long-term storage and repeat use

• Centromere visualization in high-resolution FISH
• Chromosome enumeration for diagnostics
• Prenatal/postnatal karyotyping
• Genome stability testing in stem cell research
• Cancer cytogenetics and mutation screening
• Automated or manual FISH image analysis

• 5 nmole CENPB-Alexa488 PNA probe
• FISH reconstitution and usage instructions
• Technical support resources

Need help setting up Alexa Fluor 488 for your FISH platform? Contact our team for filter recommendations and hybridization help.