F3002 – CENPB-Cy3 – 5 nmole

$295.00

Catalog Number: F3002
Product Name: CENPB-Cy3
Description: CENPB Pan-Centromere PNA Probe, Cy3 labeled
Size: 5 nmole
Label: Cy3 (Red fluorescence)
Target: ATTCGTTGGAAACGGGA (CENPB-binding region of centromere minor satellite DNA)
Purity: >95% (HPLC)
Form: Lyophilized
Application: Centromere FISH, karyotyping, Q-FISH control
Storage: –20°C, protect from light

Category:

Product Description

CENPB-Cy3 is a pan-centromere PNA probe labeled with Cy3, emitting strong red fluorescence for the detection of human centromeric DNA. It binds to the conserved CENPB binding region, enabling precise chromosome visualization in both metaphase and interphase preparations.

The PNA backbone allows for stronger hybridization and lower background noise compared to DNA probes, making it a reliable option for clinical cytogenetics, genetic screening, and chromosome enumeration.

Key Features

  • Universal detection of all human centromeres
  • Cy3 red label ensures vivid fluorescence in imaging
  • PNA chemistry for high specificity and stability
  • Effective in metaphase and interphase spreads
  • Optimized for automated and manual FISH platforms
  • Low background and excellent contrast

Applications

  • Centromere visualization in karyotyping
  • FISH-based chromosomal analysis
  • Chromosomal instability and aneuploidy studies
  • Pre-implantation genetic testing
  • Cytogenetic research and clinical diagnostics
  • High-sensitivity detection of centromere sequences

What’s Included

  • 5 nmole CENPB-Cy3 probe
  • Reconstitution and FISH usage instructions
  • Free access to expert technical support

Support

Need help selecting the best filter or probe combinations? Contact our support team for expert FISH setup recommendations.

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