F3002 – CENPB-Cy3 – 5 nmole

CENPB-Cy3 is a pan-centromere PNA probe labeled with Cy3, emitting strong red fluorescence for the detection of human and mouse centromeric DNA. It binds to the conserved CENP-B binding region, enabling precise chromosome visualization in both metaphase and interphase preparations.

The PNA backbone allows for stronger hybridization and lower background noise compared to DNA probes, making it a reliable option for clinical cytogenetics, genetic screening, and chromosome enumeration.

• Universal detection of all human and mouse centromeres except Y chromosomes
• Cy3 red label ensures fluorescence in imaging
• PNA chemistry for high specificity and stability
• Effective in metaphase and interphase spreads
• Optimized for automated and manual FISH platforms
• Low background and excellent contrast

• Centromere visualization in karyotyping
• FISH-based chromosomal analysis
• Chromosomal instability and aneuploidy studies
• Pre-implantation genetic testing
• Cytogenetic research and clinical diagnostics
• High-sensitivity detection of centromere sequences

• 5 nmole CENPB-Cy3 probe
• Reconstitution and FISH usage instructions
• Free access to expert technical support

Need help selecting the best filter or probe combinations? Contact our support team for expert FISH setup recommendations.